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시험관

Publications

2024

"CRISPR-based editing strategies to rectify EYA1 complex genomic rearrangement linked to haploinsufficiency." (2024)  MOLECULAR THERAPY NUCLEIC ACIDS.  35,  2

"Precise editing of pathogenic nucleotide repeat expansions in iPSCs using paired prime editor."  (2024)  NUCLEIC ACIDS RESEARCH.  52,  10

2023

"Integrated NLRP3, AIM2, NLRC4, Pyrin inflammasome activation and assembly drive PANoptosis." (2023) CELLULAR & MOLECULAR IMMUNOLOGY.  20,  12

"β-arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4." (2023)  CELL DEATH & DISEASE.  14,  7

"FFAR2 antagonizes TLR2-and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-kappa B." (2023)  CELL AND BIOSCIENCE.  13,  1

 "DNA double-strand break-free CRISPR interference delays Huntington’s disease progression in mice."  (2023) COMMUNICATIONS BIOLOGY.  6,  1

 "Targeted genomic translocations and inversions generated using a paired prime editing strategy."  (2023) MOLECULAR THERAPY.  31,  1

2022

"Targeted genomic translocations and inversions generated using a paired prime editing strategy" MOLECULAR THERAPY (2022)

"Expanded targeting scope of LbCas12a variants allows editing of multiple oncogenic mutations" MOLECULAR THERAPY NUCLEIC ACIDS (2022)

2015~2020

1. D. Kim et al., Unbiased investigation of specificities of prime editing systems in human cells NAR (2020) IF: 11.5
2. D. Kim et al., Genome-wide specificity of dCpf1 cytidine base editors. Nature communications (2020) IF: 12.1
3. D. Kim et al., Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases. Annual Review of Biochemistry (2019) IF: 30.3
4. D. Kim et al., Genome-wide target specificity of CRISPR RNA-guided adenine base editors. Nature Biotechnology (2019) IF: 31.9
5. D. Kim et al., Genome-wide target specificities of CRISPR RNA-guided programmable deaminases. Nature Biotechnology 35, 475-480 (2017) IF: 31.9
6. D. Kim et al., Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nature Biotechnology 34, 863-868 (2016) IF: 31.9 

7. D. Kim et al., Digenome-seq: Genome-wide Profiling of CRISPR-Cas9 Off-target Effects in Human Cells. Nature Methods 12, 237-243 (2015) IF: 28.5

유전자교정 연구실

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