We are working to develop and improve CRISPR-based genome editing technologies.
Our current research focuses on profiling and improving the genome-wide specificity of CRISPR systems such as programmable nucleases, Base editors, and Prime editors.

Major Areas of Research

• Evaluating and enhancing target specificity of CRISPR systems

• Genome editing for disease modeling and gene therapy

• CRISPR screens for the identification of therapeutic targets

• Development of a new CRISPR genome editing system