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We are working to develop and improve CRISPR-based genome editing technologies.
Our current research focuses on profiling and improving the genome-wide specificity of CRISPR systems such as programmable nucleases, Base editors, and Prime editors.
Major Areas of Research
1. Evaluating and enhancing target specificity of CRISPR systems
2. Genome editing for disease modeling and gene therapy
3. CRISPR screens for the identification of therapeutic targets
4. Development of a new CRISPR genome editing system

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